- W. M. Salmon
- P. D. Sanders
- William E. Sanders
- Col. Marion Sanson
- Dr. Bacon Saunders
- Robert Savage
- Robert E. Sawdon
- J. N. Saylor
- Dr. A. O. Scarborough
- Alfred Charles Schneider
- John W. Schrock
- Dr. Michael P. Schuster
- Ernest V. Schrimsher
- Judge David K. Scott
- George B. Scott
- Howard Coleman Scott
- Rolen Scott
- Samuel Egnew Scott
- Alexander J. Seale
- John Searl
- John W. Seek
- Ludwig Shaeffer
- Alfred L. Sharpe
- Mrs. H. L. Shelby
- William Enos Sherrill
- William M. Shields
- James W. Shirley
- R. A. Short
- William S. Short
- William A. Shown
- Charles J. Shumake
- John H. Shurbet
- David Henry Sigmon
- Williamson Burton Simpson
- Samuel Byron Slone
- Mary J. Slusser
- Rev. James M. Small
- Alfred G. Smith
- Benjamin L. Smith
- Ervin B. Smith
- Erwin J. Smith
- J. P. Smith
- Col. J. Peter Smith
- J. M. Smith
- Judge James Tillman Smith
- Judge Mike E. Smith
- Dr. Samuel L. S. Smith
- William Cory Smith
- William G. Smith
- H. B. Smoot
- Beverly Edgar Sparks
- Dr. George Sparks
- John Speer
- Capt. George Spiller
- James H. Spivey
- Langdon S. Spivey
- Judge Morris A. Spoonts
- Thomas H. Springer
- Judge Samuel H. Sprott
- Capt. Henry F. Stacy
- James Tambling Stallings
- William H. Stanfield
- Marvin W. Stanton
- Barton H. Starr
- C. H. Steele
- D. A. Stephenson
- Judge Albert Stevenson
- Rufus K. Stewart
- Ulysses S. Stewart
- Walter Preston Stewart
- A. N. Stiles
- Will Stith
- Thelma Stone
- George W. Strain
- James F. Strange
- Dr. Sneed Strong
- James N. Stuart
- Dr. Leonidas A. Suggs
- Samuel H. Sutherland
- John F. Swayne
- Orlando L. Sweet
- Thomas F. Stewart
- Thomas Flinn Sweazea